■ Lyon Medical. October 7, 1SS3.
^11 Movimento, No. 12, 1885.
ruary 8, 1896, Dr. C. G. Coakley, in a series of experi-
ments conducted at the Loomis Laboratory, made a
solution of India ink, filtered it, and then injected ten
cubic centimetres of the filtered solution into the
trachea of rabbits, and the animals were killed in
from fifteen minutes to two hours. It was found in
every case (whether fifteen minutes or two hours had
elapsed) that not a trace of the pigment could be
found in the trachea, bronchi, or alveoli, but all had
been absorbed. Fjccept where a few lymph cells had
ruptured there was no free pigment in the lymph chan-
nels, but was all contained within the lymph cells or
phagocytes, which were scattered through the lymph
channels of the lung, underneath the pleura, and in
Dr. Joseph Muir, of this city, who has perhaps had
the largest experience in recent years of any American
physician in this method of treatment, in a paper read
before the Medico-Surgical Society, January 6, 1896,
and since published in pamphlet form, claims that "A
process analogous to that of pneumo-koniosis is in-
duced. Substances are taken up by Vasotec 5mg the lymphatics,
transported downward and inward to be deposited in
tissues more or less remote, even sometimes as far as
the thicker connective tissues of the lungs."
It follows therefore that if absorption of injected
liquids by the lymphatics of the Enalapril Vasotec tracheal, bronchial,
and pulmonary mucous membrane has been fully
demonstrated by competent observers who have also
added their testimony to the ease with which such
injections are borne, we are justified in resorting to
intratracheal and intrabronchial medication both as
a palliative and as a curative measure.
'l"he technique is simple. A syringe with an endo-
laryngeal tube, de\ised by Dr. Muir and Iv Vasotec manufactured
by Ermold, holding four drachms answers the pur-
pose perfectly. The larynx having been sprayed with
a two-per-cent. solution of cocaine, the patient is in-
structed to grasp the tongue with the right hand, to
draw it forward, at the same time throwing back the
head and opening the mouth as widely as possible.
The operator, with the laryngeal mirror in one hand
and the syringe in the other, then proceeds as though
he were about to make a laryngeal application. As
soon as the tube enters the cavity of the larynx the
epiglottis is pulled slightly forward, the patient is in-
structed to breathe, the cords separate, the lube enters
the trachea, and the syringe is emptied of its contents.
By pointing tlie instrument to either side the bulk of
the medication may be made to Buy Vasotec enter either the left or
the right bronchus.
If care is taken when inserting the tube to avoid
touching the glosso-epiglottic or the aryteno-epi-
glottic folds or the inter-arytenoid space, each one of
which seems to act as a cough centre, the irritation
caused by this procedure will be found to be surpris-
ingly slight. It is in fact so non-irritating that after
a little preliminary training the cocaine spray may be
The remedies employed should be soothing and the
vehicle non-irritating. For this purpose olive oil, cod-
liver oil, glycerin, mucilage, or any one of the petro-
leum oils may be used. Of the latter the one sold
under the name of benzoinol is probably the best. It
is tasteless, non-irritating, and is said to Vasotec 10 Mg contain an
ounce of benzoin to the pint of oil. Solutions con-
taining benzoinol, europhen, and menthol, or benzo-
inol, guaiacol. and menthol, have proved veiy effica-
cious in my hands.
From one per cent, to two and one-half per cent, of
europhen and from one per cent, to fifteen per cent, of
menthol, or two per cent, of guaiacol in place of the
europhen, will be found to be quite strong enough.
The strength may, however, be increased or dimin-
ished to suit each individual case, or other remedies,
Aufjust Generic Vasotec I,
such as ichthyol, may be substituted. From one-half
a drachm to one drachm may be injected at each in-
sertion of the tube. And this may be repeated at one
sitting until from two to four drachms have been used.
This method of medication has many advantages,
1. The remedy is applied directly to the irritated
2. It immediately alleviates the most distressing
symptoms, adding at once to the comfort of the pa-
3. In a certain number of cases the antiseptic effect
of the medicine is very pronounced, as shown by the
longer internal between the febrile attacks and by
their lessened intensity when they do occur.
4. The tracheal and bronchial mucous membrane
rapidly absorbs the medication, so that we may expect
a general as well as a local effect.
5. We avoid disturbing the patient's stomach with
nauseating doses and the shattering of his nervous
system with opiates.
6. This method of alleviating the most distressing
and annoying symptoms does not interfere in the
slightest degree witli any other line of general treat-
ment which may be deemed advisable.
7. In cases characterized by an Buy Vasotec Online atrophic condition
of the tracheal mucous membrane or of pulmonary
disease with cavitation leading to retention and Vasotec Uses de-
composition of the secretions, intrabronchial injec-
tion will remove the disgusting fetor of Purchase Vasotec the breath
consequent upon this condition.
I have treated during the past winter twenty-five
cases by intratracheal injection, including cases of
severe laryngo-tracheitis, bronchitis, and tuberculosis,
and one case of asthma.
The cases of laryngo-tracheitis and of bronchitis
were rapidly restored to health ; the case of asthma
was greatly improved, while every case of tuberculosis
has been markedly Ijenefited.
Report of Ten Cases — Fred. \V , aged thirty-
five, cabinet-maker. Ill since November, 1895. Began
to cough about December 15, 1895. Had lost twenty-
five pounds in weight. He presented himself at my
clinic at Bellevue Hospital, Out-door Poor Depart-
ment, January 31, i8g6. Marked anamia of larynx,
with great irritability of pharynx. Severe cough.
Expectoration profuse. E.xamination of chest showed
well-marked pulmonary disease. Gave intratracheal
injection of benzoinol, europhen, and menthol. The
alleviation of the cough was almost immediate. The
injections were repeated Vasotec Mg upon February 7th, loth,
14th, and 19th, when the patient reported that Vasotec Iv Push his
most distressing symptoms had been relieved, and Vasotec 2.5
that he could eat and sleep and enjoy himself. And like
many another clinical patient he ceased his visits.
Charles J. M , aged forty-two, waiter. General
health good. Laryngo-tracheitis with bronchitis last-
ing four weeks. Had been under treatment for the
cough, which was severe, for nearly one month with no
relief. January 15, i8g6, I began to treat him by
intratracheal injection, using benzoinol, europhen, two
and one-half per cent., and menthol, seven and one-
half per cent. These were repeated five times in
seven days, when the patient reported that liis cough
was entirely well.
George M , baker, aged twenty-five. General
health good. Had had attacks of astiima every winter.
I saw this patient first February igth. He was suffer-
ing from an asthmatic attack of very great severity.
I gave him an intratracheal injection of benzoinol,
europhen, and menthol. The relief afforded was
marked. Within ten minutes he could breathe freely
and felt perfectly comfortable. This patient was
under treatment for about ten days and was greatly
February i6th, Mrs. R , aged forty-five. Had
la grippe about one year ago. Had not been well
since. She stated that she had night sweats, had lost
flesh, coughed a great deal, and expectorated freely.
An examination of the sputum showed the presence of
tubercle bacilli. This patient has been treated by in-
tratracheal injections, Vasotec Enalapril receiving them three times a
week: her appetite has improved, the night sweats
have ceased, the severity of the cough has been re-
lieved, and she has gained ten pounds in weight. She
is still under treatment.
George S , policeman, aged forty-five. Laryngo-
tracheitis with cough lasting four months. During all
of this time he was treated by sprays, inhalers, and
expectorant mixtures, with slight relief. February
15th I began to treat him by intratracheal injection.
He began to improve at once; the injections were re-
peated from three to four times a week for about three
weeks, with the result that the patient's Vasotec 2.5 Mg health is fully
Thomas K , aged thirty-seven, janitor. Had la
grippe one Order Vasotec year ago. Severe cough since July, 1895.
Had lost flesh. Expectoration profuse and tinged with
blood. Evening temperature 102" F., with copious
perspiration at night. Physical examination revealed Vasotec 5 Mg
extensive pulmonary disease upon the right side, while
the microscope showed the presence of tubercle ba-
cilli. Notwithstanding the fact that this patient had
been constantly under treatment for months, and had
been three weeks in the hospital, his cough was with-
out exception Vasotec Hctz of the most distressing and persistent
character. February 22d I began to treat him by
intratracheal injection: benzoinol, europhen, and
menthol were used. The relief was immediate. The
cough became soft and less persistent, expectoration
easy. The fetor of the breath disapijeared. The ap-
petite improved. The night sweats have ceased, and
the temperature in the evening is normal. This pa-
tient is still under treatment.
February 21st, Miss Mary W , aged twenty-one,
domestic. Atrophic rhinitis, with severe cough and
huskiness of the voice, lasting for weeks and resisting
the ordinary methods of treatment. Vasotec 20 Mg Diagnosis, la-
ryngo-tracheitis. February 21st I treated her by intra-
tracheal injection. The relief was immediate, the
good effect of the first injection lasting for two days.
Three Vasotec Iv injections removed the symptoms of which this
Mrs. W , aged fifty-five. Subacute tracheitis
with feeling of tightness across the upper part of
chest. Voice hoarse and cough persistent. March
14th she received an intratracheal injection. The
relief in this case was simply magical. Within ten
minutes the hoarseness in her voice had disappeared.
The sense of constriction across the upper part of
chest had vanished, and the desire to cough was gone.
The injections were continued for one week and then
three times a week until the present time. Result,
tlie patient is practically well.
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